“Finally, I would highlight that our new product portfolio will expand this quarter with the addition of repotrectinib next month and, upon completion of the Mirati transaction, Krazati.”

In context

“e of this important treatment. For Zeposia, performance remained strong in MS. In UC, access has been a constraint that will require continued focus to unlock future growth. Again, Adam can provide additional context. Taken together, we now expect sales from this portfolio to be $3.5 billion in 2023. This is slightly lower than we had expected at the start of this year. Looking forward, we see continued growth. In the medium term, we do expect to achieve greater than $10 billion in sales for this portfolio in 2026, rather than 2025. The commercial team is laser focused on building on the momentum of performance in the quarter and, importantly, accelerating performance where necessary. We are also further increasing our investment behind selective brands to ensure performance accelerates. Finally, I would highlight that our new product portfolio will expand this quarter with the addition of repotrectinib next month and, upon completion of the Mirati transaction, Krazati. Turning now to our R&D engine on Slide 8, as I mentioned last month, we have exciting opportunities to strengthen our pipeline and deliver more important medicines to patients across therapeutic areas, including expanding our registrational pipeline from six to 12 assets over the next 18 months. Since our R&D day, we’ve continued to make progress. In oncology for Opdivo, we’ve delivered several growth drivers, including U.S. approval in stage 2 adjuvant melanoma, presentation of positive data for peri-adjuvant lung with CheckMate -77T and for first line bladder cancer with CheckMate -901, and importantly we’ve met the co-primary endpoints for the sub-cutaneous nivolumab trial, CheckMate -67T. This has the potential to open a regulatory approval in indications that constitute approximate”