“This year, it's really important to focus on increased paid commercial prescriptions for Sotyktu.”

In context

“reas. The first is driving demand at the top of the funnel, and the second is, securing access. And of course, as you mentioned, pulling through those patients from bridge to commercial and we're making progress against both. You heard from David, when you normalize sales, excluding clinical trial, orders, net sales increased about 40% versus Q3. And access is critically important in this highly competitive market to drive commercial sales. So we've secured ESI and now Cigna in a one-step position that adds another 40 million lives approximately to complement CVS, which is in a zero step position, will continue to be this year, and that's approximately 25 million lives. And we're actively negotiating with other payers, and look forward to updating you on additional progress in due course. This year, it's really important to focus on increased paid commercial prescriptions for Sotyktu. We will continue to build volume from both new patients that are going to move directly onto Sotyktu at the specialty pharmacies, which, quite frankly, become easier with the improved access that we have now, as well as moving patients out of bridge and onto commercial products. David talked about where we are today, but in Q1, we expect to see around 10,000 paid prescriptions for Sotyktu. And he also mentioned, there will be an increase in gross net due to broader rebating, which was needed to secure improved access, that impacts net sales in Q1. But we expect to see good momentum in growing our base of paid prescriptions this year. And we plan to get roughly double that level around 20,000 prescriptions in Q4. And that volume momentum will more than offset the gross-to-net reset in Q1 a”