“We plan to initiate 7 Phase III programs starting this year on Coben, clearly illustrating that we'll continue to invest in our pipeline.”

In context

“g reflexive prescribing habits, and that's going to take some time. So we would expect to see continued strong uptake through 2025. And as we said, with the ramp back half of this year. But taken together, we are really pleased with what we're seeing so far, and we plan to make this a very big product for the company over time. Christopher Boerner: Thanks, Adam. And Chris, with respect to the second part of your question on the cost program, let me say a few things. First, as you think about this cost program keep in mind that our focus as a company continues to be on investing for growth. That's investing in the products that we have today, investing in the pipeline, both the late-stage pipeline as well as promising early areas of science. And maybe just give you quick vignettes on that. We plan to initiate 7 Phase III programs starting this year on Coben, clearly illustrating that we'll continue to invest in our pipeline. And then Adam can speak to this, but we made significant up investments in commercial last year which explains, we believe part of the progress that we've made on products like CEMZYOS, OPDIVO and BRIAN. So investing in growth is a priority for us, and that's the top priority. With respect to the cost programs, just a bit of context. As we were executing on last year's program, we cataloged a number of opportunities for us to become a more agile company, to become more nimble and speedy in terms of how we operate. And given where we are on that program as well as where we are with respect to LOEs, we think that it makes sense for us to capitalize on those opportunities now. So that's really driven the timing of this announcement, and we think it puts us in a good position going forward. W”