“Longer-term, we anticipate peak sales of Vyalev to exceed $1 billion.”

In context

“well as the other approved indications. Finally, we are very excited for the recent U.S. approval of Vyalev, a transformative therapy for patients with advanced Parkinson’s disease, who are uncontrolled on oral therapy alone. As a less invasive, non-surgical delivery system that can provide meaningful improvements in on-time and off-time, we believe Vyalev has the potential to significantly expand use beyond current device aided therapies. Sales in the U.S. for Vyalev are expected to ramp gradually over the next several quarters as we work to establish the appropriate Medicare coverage and benefit determination. At the same time, we are very encouraged by the interest in uptake internationally, where we have approval now in 35 countries with several thousand patients already on treatment. Longer-term, we anticipate peak sales of Vyalev to exceed $1 billion. So overall, I’m very pleased with the continued commercial execution and performance across the therapeutic portfolio. And with that, I’ll turn the call over to Carrie, for additional comments on aesthetics. Carrie? Carrie Strom: Thank you, Jeff. Third quarter global aesthetics sales were more than $1.2 billion representing growth of 1.8% on an operational basis. In the U.S, aesthetic sales of $791 million increased by 3.9%, driven by growth from Botox Cosmetic as well as other brands across our broad portfolio. U.S. Botox Cosmetic sales were $414 million an increase of 6.5% versus the prior year. Favorable pricing dynamics and facial toxin market growth more than offset modest share erosion. Botox Cosmetics remains the clear market leader. U.S. Juvederm sales were $105 million. Juvederm’”