“Total oral CGRP revenues of $2.2 billion an increase of $100 million reflecting strong prescription demand.”

In context

“mately $59.7 billion an increase of $700 million. This reflects an estimated 0.6% unfavorable impact from foreign exchange on full year sales growth. This updated revenue forecast includes the following approximate assumptions for several of our key products. We now expect Skyrizi global revenues of $16.5 billion an increase of $600 million reflecting share gains in psoriasis and IBD. Rinvoq global sales of $8.2 billion, an increase of $300 million reflecting momentum across all approved indications. US Humira revenues of $3.5 billion a decrease of $500 million reflecting higher erosion from biosimilar competition as well as further molecule compression. BOTOX Therapeutic global sales of $3.6 billion, an increase of $100 million reflecting growth in chronic migraine and other indications. Total oral CGRP revenues of $2.2 billion an increase of $100 million reflecting strong prescription demand. Imbruvica global revenues of $2.8 billion an increase of $100 million reflecting lower erosion. Venclexta global sales of $2.7 billion an increase of $100 million reflecting continued uptake in both CLL and AML across our key countries. And for aesthetics, we now expect global sales of $5.1 billion as we are moderating our assumptions for market growth globally. As a result, total sales guidance for BOTOX and Juvederm will each be lower by roughly $100 million. Moving to the P&L for 2025, we continue to forecast full year adjusted gross margin of approximately 84% of sales and adjusted SG&A expense of approximately $13.2 billion. We now expect adjusted R&D expense of approximately $8.9 billion reflecting additional investment in our robust pipeline for long term growth. We also now antici”