“I think we remain on track for a filing early next year based on these pivotal data, and we look forward to sharing those results at that congress.”

In context

“ee more of the same now with longer follow-up and with more patients. We've expanded those cohorts and do believe that we're on track to deliver pivotal data in that first indication, which is in the BCG nonresponsive patients recollect that in early bladder non-muscle invasive bladder cancer. Standard care is this attenuated micro bacteria BCG. Unfortunately, fewer than half patients receive -- achieve a complete response. And the therapy is -- has tolerability problems to say the least where patients feel like they have a chronic urinary tract infection. The discontinuation rate with TAR200 has been very low. So we're very delighted with the excellent tolerability profile as well as these impressive deep efficacy, deep and durable efficacy. So yes, so please watch that AUA presentation. I think we remain on track for a filing early next year based on these pivotal data, and we look forward to sharing those results at that congress. Operator: Thank you. Next question is coming from Matt Miksic from Barclays. Your line is now live. Matthew Miksic: Hi, thanks so much for taking the question. So a follow-up maybe on some of the device trends, in particular, cardio and EP very strong in the quarter. Wondering if you could provide some color kind of geographically as to how some of the product launches have either driven overseas or competitive environment in the U.S. has affected U.S. performance so far? And then just one quick one on Ortho, if I could. Timothy Schmid: Sure, Matt. Firstly, let me start on cardio. As Joaquin mentioned, we've made a lot of progress in building out our portfolio. And until recently, we only participated in one high-growth category within cardiovascular and that being electrophysiology, whic”