“Yes. As I said in my prepared remarks, we expect data at the later part of this year.”

In context

“oral drugs in this class can have a profound effect on weight loss. Of course, one needs to be maybe a little bit caution to drive weight loss too far, as you have seen also some concerns in public media about side effects that may arise from that. So we will really integrate all of that data and make a decision, and we really look forward to that moment. Operator: Our next question will come from Evan Seigerman with BMO. Evan Seigerman: Kind of a follow-up from Umer’s, I want to focus on the GLP-1 franchise. Can you talk about the competitive profile of danuglipron in its current form, considering safety, twice-daily dosing and efficacy? And maybe remind us on the time lines to potentially get more on a once-daily formulation of this asset? Dr. Albert Bourla: Mikael? Dr. Mikael Dolsten: Yes. As I said in my prepared remarks, we expect data at the later part of this year. We are absolutely encouraged and confident that it has a different profile when it comes to adverse events as the danuglipron that we sold. So we don’t see that as an issue. And I spoke to that we will put together the totality of data to pending readout, prepare a potential Phase 3 program. And it’s a very big sector, diabetes and obesity. We have considerable expertise in treating cardiometabolic patients. So, we look forward to share more data and more plans with you as we move to further quarter. Thank you for your great interest in this important space. Operator: Next, we have Terence Flynn with Morgan Stanley. Terence Flynn: Maybe two for me. Dave, I was just wondering how we should think about steady-state operating margin here. Looking back pre-COVID, the Company was around mid- t”