“And we do have an interim analysis later this year for the CIFFREO trial.”

In context

“iability and exposure, which typically reduce GI side effects that have been seen as limiting this drug. So that’s why I can see a potential twofold advantage of MR goes from twice a day to once a day and may also help uniquely to create a tolerability profile within the structure of GLPs. [Ph] DMD gene therapy, I’m encouraged that FDA took a very positive angle on that drug when it comes to its urgency to get into the market. Chris, you and I have worked very closely on that, and we expect today we’ll look relatively soon to conclude the trial. I’ll also ask Chris to pitch in on it. Dr. Chris Boshoff: Thank you, Mikael. So the DMD program is obviously very important for us, not just for the importance of gene therapy but for patients and families with this absolutely devastating disease. And we do have an interim analysis later this year for the CIFFREO trial. The CIFFREO trial, all patients have now been enrolled in the study. The interim analysis will be based not on a surrogate biomarker end point but on truly functional end point. So, we believe that’s the best way to measure the benefit of gene therapy in this disease is with a functional end point. And that should come later this year, and we’ll update you with the final analysis for the study then in 2024. Dr. Albert Bourla: That was terrific. I just wanted to add that we have, like you heard Sarepta, ample biomarker that look very robust in our hand. But as Chris said, we want to provide patients with even more experience about the potential benefit. Operator: Next, we have Kerry Holford with Berenberg. Kerry Holford: A couple of questions [Technical Difficulty] savings. It’s clear that”