“over the course of this year, we expect it to grow rapidly, driven primarily by increased demand in our top 100 accounts as well as increased adoption in the community setting, which I think positions ELREXFIO very, very well for the future as we expand indications into earlier lines of therapy in '26 and beyond.”

In context

“getting some of the earlier line data that you're expecting later this year from the Phase 3 trial? And then on danuglipron, on the dose optimization study, can you just kind of clarify how much data you're going to share later this quarter? Will we get weight loss data? Will we get tolerability data? How much data will be in the initial press release? Thank you. Albert Bourla: Thank you. Aamir? Aamir Malik: Yes. We're very excited about the momentum on ELREXFIO. We continue to see increase in share in new patient starts quarter-over-quarter, in the class. And the uptick also does include community receptivity and awareness and new account adoptions. And obviously, with the whole slew of trials, assuming they're successful to follow, I think there's a lot of momentum behind ELREXFIO. And over the course of this year, we expect it to grow rapidly, driven primarily by increased demand in our top 100 accounts as well as increased adoption in the community setting, which I think positions ELREXFIO very, very well for the future as we expand indications into earlier lines of therapy in '26 and beyond. Albert Bourla: Thank you. And myself, I was quite impressed with community oncologist uptake of this product as quickly as it happened in the U.S. But also, we have very good news for ELREXFIO in international market. Alexandre? Alexandre de Germay: Yes, indeed ELREXFIO was commercially launched in already six markets in 2024, out of our top 15 markets, quite fast penetration. And of course, in 2025, we are expecting to get an additional 18 markets and four additional of our top 15 markets will launch this year. But the combination of the expand access plus the performance of the brands where we already have introduced the product gives us great confidence for accelerated growth. And to give you a sense, Japan is the second largest market outside of the U.S., and we had a significant and”